Technology area

Neural interface

230 funded awards, $140.5M total, FY2023-FY2025.

Data current as of 2026-05-11

Pattern read

Neural interface is a focused tag at 230 records / $140M. NINDS leads with 43 (motor and sensory restoration work), NIMH at 40 (closed-loop psychiatric devices, deep-brain stimulation), and NIA at 29 (cognitive interfaces, dementia-relevant). Median award is $499K, near the dataset median. Concentration is higher than most tags at 9.6%; a smaller pool of specialized firms appears repeatedly. STTR (R41 at 36) participation is notable. R44/R43 ratio is roughly 2:1.

Fit indicators

  • Three-IC anchor (NINDS, NIMH, NIA). Indication-specific framing is mandatory; 'neural interface platform' framing has historically been weak.
  • Strong STTR presence; academic-engineering structures have been viable.

Watchouts

  • Concentration is higher than average (~10% top three). The field is specialized; new entrants need a clear differentiator.
  • Reviewers in this space have specific device-experience expectations. Generic ML or engineering teams without neuroscience grounding have not fared well.

Where the money sat, by Institute / Center

IC funding decisions are set by portfolio priorities, NOFO scope, and program-officer judgment. These are funded records, not predictions of future funding.

ICNameRecordsMedian award
NS (NINDS) National Institute of Neurological Disorders and Stroke 43 $485,026
MH (NIMH) National Institute of Mental Health 40 $834,470
AG (NIA) National Institute on Aging 29 $499,961
DC (NIDCD) National Institute on Deafness and Other Communication Disorders 26 $307,417
GM (NIGMS) National Institute of General Medical Sciences 16 $915,555
HL (NHLBI) National Heart Lung and Blood Institute 15 $488,080
HD (NICHD) Eunice Kennedy Shriver National Institute of Child Health and Human Development 11 $876,333
DA (NIDA) National Institute on Drug Abuse 10 $359,869
AI (NIAID) National Institute of Allergy and Infectious Diseases 9 $298,938
EY (NEI) National Eye Institute 8 $344,089
CA (NCI) National Cancer Institute 5 $709,898
DK (NIDDK) National Institute of Diabetes and Digestive and Kidney Diseases 5 $854,130
HG (NHGRI) National Human Genome Research Institute 3 $1,107,445
AA (NIAAA) National Institute on Alcohol Abuse and Alcoholism 2 $402,766
ES (NIEHS) National Institute of Environmental Health Sciences 2 $422,812
OD NIH Office of the Director 1 $416,925
MD (NIMHD) National Institute on Minority Health and Health Disparities 1 $5,080
NR (NINR) National Institute of Nursing Research 1 $284,317
AT (NCCIH) National Center for Complementary and Integrative Health 1 $241,102
EB (NIBIB) National Institute of Biomedical Imaging and Bioengineering 1 $305,000
AR (NIAMS) National Institute of Arthritis and Musculoskeletal and Skin Diseases 1 $745,511

FOA / NOFO routes

Opportunity number prefixes: PA = Parent Announcement (broad, omnibus, multiple ICs), PAR = Parent with Special Review, PAS = Parent with set-aside funds, RFA = Request for Applications (targeted, single-IC, fixed budget). Status unknown means the pipeline has not verified whether the FOA is currently posting awards; the SBIR omnibus has been in reauthorization gap during this window. See the glossary for full definitions.

OpportunityStatusRecords
PA-22-176 unknown 29
PA-23-230 unknown 26
PA-21-259 unknown 16
PA-22-178 unknown 12
PA-24-245 unknown 10
PA-21-260 unknown 8
PA-24-247 unknown 8
PA-21-262 unknown 8
PA-22-177 unknown 7
PAS-22-196 unknown 7
PA-20-272 unknown 7
PAR-21-266 unknown 7
PA-20-260 unknown 6
PA-21-345 unknown 6
PA-23-233 unknown 5
PA-20-262 unknown 4
PA-23-232 unknown 4
PA-24-246 unknown 4
PAR-22-073 unknown 4
PAS-19-316 unknown 4
PA-23-231 unknown 3
PA-18-871 unknown 3
PAR-18-801 unknown 2
RFA-NS-20-010 unknown 2
RFA-MD-22-004 unknown 2
PAR-23-311 expired 2
PAS-22-197 unknown 2
PA-22-179 unknown 2
RFA-DA-22-001 unknown 2
RFA-AG-22-014 unknown 2
PAR-21-114 unknown 2
PA-19-272 unknown 2
PA-18-573 unknown 2
PAR-24-044 expired 1
RFA-AA-24-001 unknown 1
RFA-CA-24-023 unknown 1
PA-25-212 unknown 1
PA-24-248 unknown 1
RFA-MD-23-003 unknown 1
PAR-23-213 unknown 1
RFA-NS-23-006 unknown 1
PA-18-591 unknown 1
RFA-DA-19-020 unknown 1
PA-18-566 unknown 1
PAS-19-317 unknown 1
PA-18-870 unknown 1
PAR-19-333 unknown 1
PA-20-265 unknown 1
PA-18-574 unknown 1
RFA-ES-21-005 unknown 1
RFA-NS-20-011 unknown 1
RFA-DA-23-020 unknown 1
RFA-DA-23-021 unknown 1

Comparable funded projects

ApplIDFYICTitleOrganizationAmount
10933016 2025 CA Validation of a lab-free low-cost screening test for prevention of cervical cancer: automated visual evaluation DL ANALYTICS, LLC $709,898
11004965 2025 DC Open Source Hearing Assessment System for Open Science CREARE, LLC $1,174,451
11017717 2025 MH Scaling Volumetric Imaging, Analysis and Science Communication Using Immersive Virtual Reality ISTOVISR $1,196,536
11042227 2025 MH XCSITE 300: Cloud-Enabled Closed-Loop Transcranial Current Stimulation Device for At-Home Studies PULVINAR NEURO LLC $1,018,838
11052557 2025 DC Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation RESTOREAR DEVICES, LLC $329,169
11053642 2025 NS Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P) EVON MEDICS, LLC $1,280,870
11067358 2025 AA Study of Transcutaneous Auricular Neurostimulation as a Treatment for Alcohol Use Disorder SPARK BIOMEDICAL INC $305,545
11067689 2025 MH Validation of next-generation TMS system optimizing for widely scalable, personalized treatment of depression AMPA INC. $1,199,261

Review panels that have appeared on these records

Panel names use NIH's Center for Scientific Review (CSR) format: a 2-4 letter study-section code plus a meeting-cycle number in parentheses (e.g. ISB (12) = Instrumentation and Systems Development, cycle 12). SBIR/STTR review groups are temporary, meeting-specific bodies. The names below describe panels that have appeared on the cited funded-project records, not where future applications get assigned. NIH assigns panels at the time of submission based on the application content.

Limitations

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